Pyrimidine Pools and Macromolecular Composition of Pyrimidine-Limited Escherichia coli
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منابع مشابه
Escherichia coli DNA photolyase reverses cyclobutane pyrimidine dimers but not pyrimidine-pyrimidone (6-4) photoproducts.
The effect of purified Escherichia coli DNA photolyase on the UV light-induced pyrimidine-pyrimidone (6-4) photoproduct and cyclobutane pyrimidine dimer was investigated in vitro using enzyme purified from cells carrying the cloned phr gene (map position, 15.7 min). Photoproducts were examined both as site-specific lesions in end-labeled DNA and as chromatographically identified products in uni...
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Toluene-treated cells were used for examining excision of pyrimidine dimers in Escherichia coli strains W3110, DM845 (uvrA-), P3478 (polA-), and KS5064 (polAex1). Excision occurring in toluene-treated cells is rapid, adenosine 5'-triphosphate dependent, and requires the uvrA gene function. In strains lacking either the polymerizing or 5' leads to 3' exonucleolytic activity of deoxyribonucleic a...
متن کاملThe purine and pyrimidine metabolism of normal and phage-infected Escherichia coli.
In the Escherichia coli B-coliphage system, duplication of the “T-even” phages involves the active synthesis of desoxypentose nucleic acid (DNA) (1). This virus DNA differs in purine to pyrimidine ratio from that of the host cell (2-4) and cytosine has been reported absent in purified preparations of Tz phage (2). Although the synthesis of virus DNA proceeds mainly from nitrogen (5) and phospho...
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It has been shown previously that hydroxyuridine competitively inhibits the growth of purine-requiring mutants of Escherichia coli (1). However, the inhibition is ultimately overcome, presumably because of the destruction of hydroxyuridine. It was of interest to det.ermine whether the inhibitor is, indeed, degraded, and, if so, what structural changes produce the loss of inhibitory activity. In...
متن کاملEnzymes of the Pyrimidine Pathway in Escherichia Coli. Ii. Intracellular Localization and Properties of Dihydroorotic Dehydrogenase.
Taylor, W. Herman (Portland State College, Portland, Ore.), and Mary L. Taylor. Enzymes of the pyrimidine pathway in Escherichia coli. II. Intracellular localization and properties of dihydroorotic dehydrogenase. J. Bacteriol. 88:105-111. 1964.-Intracellular localization of three enzymes of the pyrimidine pathway in Escherichia coli was studied. Dihydroorotic dehydrogenase was found to be assoc...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1970
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.102.1.118-123.1970